Archive for March, 2009

End to rate-of-living theory of longevity

You might have, at some stage, encountered the idea that the lifespan of an animal is related to its rate of energy consumption; i.e., that the faster its metabolism, the shorter an animal lives. I’ve also heard it said that all animals get a certain number of heartbeats in life and the sooner they use [...]

Long-term L-carnitine prevents liver cancer

An article appearing recently in the World Journal of Gastroenterology penned by the team led by Professor Sayed-Ahmed from the College of Pharmacy, King Saud University, has reported on the role of carnitine in the liver during the development of liver cancer (hepatocarcinogenesis). Apparently, carnitine deficiency is a risk factor and critical to the mechanism [...]

Yeast, NuA4, Pck1p -> life extension

A press release appeared on the John Hopkins website detailing a new discovery regarding life extension in yeast. The press release can be found here: Starve a yeast, sweeten its lifespan.
To summarize, here’s what happened:

Yeast produce an enzyme complex called NuA4, which is under investigation for its DNA-repair properties.

John Hopkins researchers tested whether NuA4’s level [...]