Salk Institute researchers have identified an enzyme crucial to the life-extension effects brought about by dietary restriction. This brings us closer to identifying the initiating signal for the cascade of effects organisms experience when subject to CR conditions. Once this ‘holy grail’ is discovered, we’ll be well on the path to creating a drug that [...]

Scientists at the Buck Institute for Age Research have identified a protein that plays a key role in the life-extending effects of calorie restriction.
Press release follows:
Buck scientists identify a key protein that may explain the anti-aging and anti-cancer benefits of dietary restriction
Novato, CA, May 21, 2009. A protein that plays a key role in [...]

A press release appeared on the John Hopkins website detailing a new discovery regarding life extension in yeast. The press release can be found here: Starve a yeast, sweeten its lifespan.
To summarize, here’s what happened:

Yeast produce an enzyme complex called NuA4, which is under investigation for its DNA-repair properties.

John Hopkins researchers tested whether NuA4’s level [...]