Yuan et al. have identified another anti-cancer effect of the “longevity” protein SIRT1. By speeding the destruction of the tumor promoter c-Myc, SIRT1 curbs cell division. The study will be published online April 13 (www.jcb.org) and will appear in the April 20 print issue of the Journal of Cell Biology.
The yeast and nematode equivalents of [...]
Two commonly administered substances were today attributed with some new anti-cancer properties: tetrahydrocannabinol (THC), the main active constituent of cannabis, and docosahexaenoic acid (DHA), an omega-3 fatty acid found in fish oil.
Reported in the Journal of Clinical Investigation, THC was shown to induce human glioma (brain cancer) cell death through a process known as autophagy, [...]
An article appearing recently in the World Journal of Gastroenterology penned by the team led by Professor Sayed-Ahmed from the College of Pharmacy, King Saud University, has reported on the role of carnitine in the liver during the development of liver cancer (hepatocarcinogenesis). Apparently, carnitine deficiency is a risk factor and critical to the mechanism [...]
In a strange twist, researchers from the Sunlight, Nutrition, and Health Research Center (SUNARC) publishing in Anticancer Research have discovered that one’s risk of developing melanoma is inversely related to long-term smoking and exposure to UV light!
Which is to say, you’re less likely to get melanoma if you spend all day out in the sun [...]
Quercetin, the small molecule that typically rubs shoulders with friends like resveratrol and EpiGalloCatechinGallate (ECGC), not just in my supplements cupboard but in anti-aging experiments and SIRT-activation tests, has now been shown to reduce the risk of colon cancer by researchers funded by the U.S. Department of Agriculture and the Vegetable and Fruit Improvement Center [...]
Those brilliant minds at Tel Aviv University have discovered that Prozac, that archetypal drug for depression, enhances the effect of a common chemotherapeutic agent, doxorubicin, by a factor of ten.
Dr. Dan Peer of the Department of Cell Research and Immunology claims that Prozac works by blocking resistance to the anti-cancer drug. Specifically, it prevents the [...]
A Malaysian study has looked at the effects of a ginger extract on levels of NF-kappa-beta and TNF-alpha, two nasties associated with cancer and inflammation, and found that it reduces the levels of these in rats with liver cancer.
This is good news for lovers of ginger, such as myself. Cheers!
Ginger extract (Zingiber officinale) has anti-cancer [...]
Research has appeared today in PLoS Biology revealing that when human cells enter a state of senescence resulting from genetic damage, they release factors into their immediate environment that cause inflammation and promote cancer.
When cells experience genetic damage, for example as a result of radiation or oxidative stress, if that damage is severe enough, they [...]
Good news for green-tea drinkers and supplementers like me. The Journal of Investigative Dermatology reported a few days ago on the mechanism of the inhibition of UVB-induced skin tumor development.
The article is reasonably technical, but I’ll summarize the results here:
Green tea polyphenol (GTP) supplementation in mice prevents photocarcinogenesis (i.e., skin cancer). I’ve not mentioned this [...]
A paper that became available today in Cell from the Spanish National Cancer Centre (CNIO) reports on the anti-aging effects of telomerase in cancer resistant mice.
Traditionally, the anti-aging effects of telomerase have been poorly explored because of its unfortunate cancer-promoting activity. Consequently, the researchers genetically engineered cancer-resistant mice by up-regulating their expression of [...]