‘skin’ Archive

Topical application of chemotherapy drug improves appearance of aging skin

According to this press release, applying a fluorouracil-containing cream to the skin results in the reduction of the signs of aging. It works essentially by causing superficial damage, which the body then reacts to, healing wrinkles and age spots in the process. The mechanism seems to be similar to that of laser resurfacing.
Topical application of [...]

No link between isotretinoin and suicide

Researchers have debunked one of the most insidious myths about this much-maligned but highly beneficial drug in an article from Dermatology Times:
Isotretinoin and suicide: Epidemiological study shows no association
London, Ontario, Canada — Suicidal behavior among patients taking isotretinoin represents an uncommon, idiosyncratic phenomenon, according to the author of a recent study of nationally representative patient [...]

Results and reflections on doxycycline experiment

A little over a month ago I conducted a personal experiment where I took 25mg/day doxycycline hyclate in an effort to improve the quality of my skin by reducing collagen breakdown via the inhibition of Matrix-Metalloproteinases (MMPs).
For the duration of the experiment, I consumed approximately 25mg doxycycline in the morning on top of my usual [...]

Personal doxycycline hyclate skin experiment

Some of you may be aware that the the antibiotic doxycycline hyclate has been found to possess anti-matrix metalloproteinase (MMP) activities. MMPs are the enzymes that break down connective tissue such as collagen, and their relative increase is thought to contribute to the development of wrinkles in aged skin.
This is because, while the ability to [...]

Smoking and UV exposure reduce melanoma risk

In a strange twist, researchers from the Sunlight, Nutrition, and Health Research Center (SUNARC) publishing in Anticancer Research have discovered that one’s risk of developing melanoma is inversely related to long-term smoking and exposure to UV light!
Which is to say, you’re less likely to get melanoma if you spend all day out in the sun [...]

Green tea supplementation reduces skin cancer risk

Good news for green-tea drinkers and supplementers like me. The Journal of Investigative Dermatology reported a few days ago on the mechanism of the inhibition of UVB-induced skin tumor development.
The article is reasonably technical, but I’ll summarize the results here:
Green tea polyphenol (GTP) supplementation in mice prevents photocarcinogenesis (i.e., skin cancer). I’ve not mentioned this [...]

Mad Professor invents ‘Beauty Machine’

Professor Daniel Cohen-Or from Tel Aviv University has developed a computer program that takes a picture of your ugly face and automagically transforms it into something potentially worth looking at.
First of all, in case you’re wondering how I know he’s mad, or at least some kind of evil genius, just look at his picture!

Lead researcher [...]